Page 1 :
Drug evaluation may be defined as the determination, of identity, purity and quality of a drug., , Identity — identification of biological source of the drug., Quality — the quantity of the active constituents present., , Purity — the extent of foreign organic material present in, , a crude drug., Importance of evaluation of crude drugs:, , Determination of Biochemical variation in the drugs, , Identification of deterioration due treatment and storage, , Repoting Substitution and adulteration, as result of, , carelessness, ignorance and fraud
Page 2 :
METHODS OF DRUG EVALUATION, , The evaluation of a drug is drug done by studying its various, , properties., , The various properties are:, (1) Organoleptic evaluation, (2) Microscopic evaluation, (3) Physical evaluation, , (4) Chemical evaluation, , (5) Analytical evaluation, , (6) Biological evaluation
Page 3 :
1.Organoleptic (Morphological) Evaluation, , This refers to drug evaluation by means of organs of sense and, includes other sensory organs like color, odour, taste ,size ,shape, , and texture., , It includes the study of morphology and other sensory, , characters., , Brown colour, , Aromatic odour, , Sweet taste, , Fractured surface, , Wavy shape, , 7 to 8mm width, , 25 to 60 mm length (size), , Cinnamon, Umbelliferous fruits, Liquorice, , Cinchona, Rauwolifia, , Senna leaf
Page 4 :
(a) Study of Morphology, , It includes the visual examination of drug., , toe nne Paton, KURCHI, , 1 BARK, TURMERIC,ZINGER, , UNDERGROUND, LEAVES DIGITALIS, SAFFRON, , FLOWERS, FRUITS FENNEL, SEEDS NUX-VOMICA, RESIN ASAFOETIDA, SANDAL WOOD, , WOOD, GUMS ACACIA, ERGOT, , ENTIRE DRUG
Page 5 :
1- Shape and size., , Flowers:, , Floral parts: stigmas, corollas, anther, ovary, receptacle., Leaves and leaflets:, , Length, width, apex, margin, base, venation,, , the texture of the leaf and the hairs in upper and lower surface., The feel of the surface described as soft, hairy smooth., , Bark:, , The barks occur in three shapes:, , *Flat or curved pieces., , * Single quill., , *Double quills., , ii- Barks have two surfaces, an outer and inner., , iii- The inner surface is usually lighter in color than the outer surface, 2- Odor and taste., , Odor:, , 1-distinct 2- indistinct, , aromatic-balsamic,- spicy