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QUESTION BANK, Each question carries one mark, , Note : Encirele the alphabet which corresponds to the single best response., 1. One micrometer is equal to;, A. 10° centimeter, B. 10°) centimeter, iC © meter, D. 10-3 meter, , ite ate aad, , 2. Which of the Relowing, preperens of a particle significantly affecas |, physical, chemical and biological properties of the drug?, A. density, B. sedimentation, Cc. size j, surface area, 3. It is difficult to express the size of particles in a meaningful diamete *, reason is that the particles in a powder are:, irregular in shape }, B. irregular surface 4, C. spherical shape, D. uniform in size, 4. The type of a particle diameter obtained largely depends on:, eT eased by which it is determined Fi, B. nature of the powder \, C. procedure by which it is calculated :, D. way it is defined and described A, 5. When cumulative percent frequency on a probability scale is plotted, logarithm of the particle size, 50 percent on the probability scale, powder particle diameter of: ;, A. arithmetic mean, B. arithmetic mode, geometric mean, D. harmonic mean, 6. Which one of these distributions is more important in he, forms?, A. Gaussian, B. normal
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231, , goers, ¢. amber, weigh!, joemulti0" development of emulsions and suspensions, what type of, he, , a method is used for size distribution analysis of powders. The, * gsadvantage of this method is:, A. agglomerates can be identified, yan of powder is possible, C. large number of siéves are required, D. tedious and time consuming, (While using sedimentation method for size analysis, addition of a, deflocculating agent to @ suspension is necessary in order to:, A. accelerate the process of sedimentation, B. make the particles spherical, prevent the aggregation, . satisfy Reynolds number, } Stokes a be used, if Reynolds number is more than:, . LB, Cc 90, D. 18.0, , | Andreasen, | AL nperetus consists of:, , Ly /, hen ¢, ', owing ‘er-counter apparatus is employed for powder analysis, the, A, Sc rlerion is important:, , eG, , spe medium should be coloured, “ nag oe should be conducting, b , > *apendeg particles should be charged, he particles should be sp!, wean unter, as the particles travel through the orifice, , gituctance between the cloarodes eee, , é, , the event that, , ns for volume measurement
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232, , a‘ eh SI, A. light transmission of gas that reaches th CAL Me, B. pressure across the compacted Powder e detecto,, , C. thermal conductivity of gas acro, , SS, \D- Weight of powder when air js panned Ted acy, 15. High repose angle of the granules indicates: Bh the Pow, A. bulk density of the granules , ¥, , B. porosity of the granules, icon of the granule surface, , smoothness of the granule surface f, 16. The true density of talc is 2.7 g/cc, the bulk densit y, A. equal to 2.7 eg OF tale wa,, B. greater than 2.7 a, \C-—TEss than 2.7 ,, D. unrelated, 17. The angle of repose values are utilized to: f, A ‘asure the movement of granules from hopper to the tut, a, , tabletting/capsule machine, B. select proper containers for capsules of a given mass of pow;, C. study the absorption of drugs., D. understand dissolution of medicament, , 18. The term ‘light’ as applied to pharmaceutical powders means:, A. low bulk density Ay, , ‘B-Tow granule density ty, C. low true density, D. slightly coloured, , Bu, , i, microscope me, , 19. The type of particle diameter that is obtained by _, evaluation is:, uc projected %, B. Stokes’, C. volume ‘y, D. volume-surface 4, 20. Porosity of a porous powder is defined as: \ ‘,, A. bulk volume/void volume \, “void volume/bulk volume My, C. void volume/true volume Ny, D. true volume/bulk volume , 4
