Page 1 : y distress syndrome, glucocorticoids, , d arthritis, , mia, , nia is the decrease in all fractions, eins., following conditions:, , e, , ], starvation, liver, sctions., , F PLASMA PROTEINS, , stage, the plasma proteins are, the mesenchyme cells. In adults,, {eins are synthesized mainly from, slial cells of liver and also from, narrow, disintegrating blood cells, ssue cells. Gamma globulin is, om B lymphocytes., , ES OF PLASMA PROTEINS, ight, 69,000, 1,56,000, 4,00,000, ity, favity of the plasma proteins is, , =, , , , buffering action of the Diooe., , ™ FUNCTIONS OF PLASMA, PROTEINS, , 1. Role in Coagulation of Blood, , Fibrinogen is essential for the coagulation of, blood (Chapter 15)., , 2. Role in Defense Mechanism of Body, , The gamma globulins play an important role in, the defense mechanism of the body by acting, as antibodies. These proteins are also called, immunoglobulins (Chapter 13), , 3. Role in Transport Mechanism, , Plasma proteins are essential for the transport, of various substances in the blood. Albumin,, alpha globulin and beta globulin are responsible, for the transport of the hormones, enzymes, etc, The alpha and beta globulins transport metals, in the blood, , 4. Role in Maintenance of Osmotic, Pressure in Blood, , Plasma proteins exert the colloidal osmotic, (oncotic) pressure. The osmotic pressure exerted, by the plasma proteins is about 25 mm Hg, Since the concentration of albumin is more than, the other plasma proteins, it exerts maximum, pressure., , 5. Role in Regulation of Acid-base Balance, , Plasma proteins, particularly the albumin, play, an important role in regulating the acid-base, balance in the blood. This is because of the virtue, of their buffering action., , a