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MAULANA ABUL KALAM AZAD UNIVERSITY OF TECHNOLOGY, (Formerly West Bengal University of Technology), B.PHARM Syllabus, (Effective from 2017-2018 Admission Session), , PT 512 PHARMACOGNOSY AND PHYTOCHEMISTRY II (Theory), 45Hours, Scope: The main purpose of subject is to impart the students the knowledge of how the, secondary metabolites are produced in the crude drugs, how to isolate and identify and, produce them industrially. Also this subject involves the study of producing the plants and, phytochemicals through plant tissue culture, drug interactions and basic principles of, traditional system of medicine, Objectives: Upon completion of the course, the student shall be able, 1. to know the modern extraction techniques, characterization and identification of the, herbal drugs and phytoconstituents, 2. to understand the preparation and development of herbal formulation., 3. to understand the herbal drug interactions, , 4. to carryout isolation and identification of phytoconstituents, , Course Content:, UNIT-I 9 Hours, Metabolic pathways in higher plants and their determination, a) Brief study of basic metabolic pathways and formation of different secondary metabolites, through these pathways- Shikimic acid pathway, mevalonic pathways., b) Study of utilization of radioactive isotopes in the investigation of Biosynthetic studies., , UNIT-IE 17 Hours, General introduction, composition, chemistry & chemical classes, biosources, therapeutic, uses and commercial applications of following secondary metabolites:, , Alkaloids: Vinca, Rauwolfia, Belladonna, Opium,, , Phenylpropanoids and Flavonoids: Lignans, Tea, Ruta, , Steroids, Cardiac Glycosides & Triterpenoids: Liquorice, Dioscorea, Digitalis, Volatile oils: Mentha, Clove, Cinnamon, Fennel, Coriander,, , Tannins: Catechu, Pterocarpus, , Resins: Benzoin, Guggul, Ginger, Asafoetida, Myrrh, Colophony, , Glycosides: Senna, Aloes, Bitter Almond, , Iridoids, Other terpenoids & Naphthaquinones: Gentian, Artemisia, taxus, carotenoids, , UNIT-IL 06 Hours, Isolation, Identification and Analysis of Phytoconstituents, , a) Terpenoids: Menthol, Citral, Artemisin, , b) Glycosides: Glycyrhetinic acid & Rutin, , c) Alkaloids: Atropine, Quinine, Reserpine, Caffeine, d) Resins: Podophyllotoxin, Curcumin, , UNIT IV 10 Hours, Basics of Phytochemistry, , Modern methods of extraction, application of latest techniques like Spectroscopy,, chromatography and electrophoresis in the isolation, purification and identification of crude, drugs.

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MAULANA ABUL KALAM AZAD UNIVERSITY OF TECHNOLOGY, (Formerly West Bengal University of Technology), B.PHARM Syllabus, (Effective from 2017-2018 Admission Session), , PT 592 PHARMACOGNOSY AND PHYTOCHEMISTRY II (Practical), 4 Hours/Week, , Morphology, histology and powder characteristics & extraction & detection, of: Cinchona, Cinnamon, Senna, Clove, Ephedra, Fennel and Coriander, Exercise involving isolation & detection of active principles, , a. Caffeine - from tea dust., , b. Starch from Potato, , c. Atropine from Belladonna, , d. Sennosides from Senna, , Separation of sugars by Paper chromatography, , 4. TLC of herbal extract, , Analysis of crude drugs by chemical tests: (i) Asafoetida (ii) Benzoin, (iii) Colophony (iv) Aloes (v) Myrrh, , Recommended Books: (Latest Editions), , L,, , W.C.Evans, Trease and Evans Pharmacognosy, 16th edition, W.B. Sounders &, Co., London, 2009., , Mohammad Ali. Pharmacognosy and Phytochemistry, CBS, , Publishers & Distribution, New Delhi., , Text book of Pharmacognosy by C.K. Kokate, Purohit, Gokhlae (2007),37th, Edition, Nirali Prakashan, New Delhi., , Herbal drug industry by R.D. Choudhary (1996), Ist Edn, Eastern Publisher,, New Delhi., , Essentials of Pharmacognosy, Dr.SH.Ansari, IInd edition, Birla publications,, New Delhi, 2007, , Herbal Cosmetics by H.Pande, Asia Pacific Business press, Inc, New Delhi., A.N. Kalia, Textbook of Industrial Pharmacognosy, CBS Publishers, New, Delhi, 2005., , R Endress, Plant cell Biotechnology, Springer-Verlag, Berlin, 1994., Pharmacognosy & Pharmacobiotechnology. James Bobbers, Marilyn KS, VE, Tylor., , 10. The formulation and preparation of cosmetic, fragrances and flavours., 11. Remington’s Pharmaceutical sciences., , 12. Text Book of Biotechnology by Vyas and Dixit., , 13. Text Book of Biotechnology by R.C. Dubey.