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Welcome to the world, of, pharmacy, Scanned with CamScanner
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PHARMACIST, (Job opportunity/Work areas), Practice Settings, Other Settings, Community, Hospital, Clinical, Academics Clinical Research Regulatory, Teaching, Research, Industry, Production, Quality, Assurance, R&D, Quality, Control, Packaging, Sales &, Marketing, Regulatory, Formulation, Bulk, Drugs, Scanned with CamScanner
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BP102T. PHARMACEUTICAL ANALYSIS (Theory), 45 Hours, Scope: This course deals with the fundamentals of analytical chemistry and principles of, electrochemical anal ysis of drugs, Objectives: Upon completion of the course student shall be able to, • understand the principles of volumetric and electro chemical analysis, carryout various volumetric and electrochemical titrations, • develop anal ytical skills, Course Content:, UNIT-I, 10 Hours, (a) Pharmaceutical analysis- Definition and scope, i) Different techniques of anal ysis, ii) Methods of expressing concentration, iii) Primary and secondary standards., iv) Preparation and standardization of various molar and normal solutions-, Ox alic acid, sodium hydroxide, hydrochloric acid, sodium thiosulphate,, sulphuric acid, potassium permanganate and ceric ammonium sulphate, (b)Errors: Sources of errors, types of errors, methods of minimizing errors,, accuracy, precision and significant figures, (c)Pharmacopoeia, Sources of impurities in medicinal agents, limit tests., UNIT-II, 10 Hours, • Acid base titration: Theories of acid base indicators, classification of, acid base titrations and theory involved in titrations of strong, weak, and, very weak acids and bases, neutralization curves, • Non aqueous titration: Solvents, acidimetry and alkalimetry titration and, estimation of Sodium benzoate and Ephedrine HCI, UNIT-III, 10 Hours, • Precipitation titrations:, Volhard's, Fajans method, estimation of sodium chloride., • Complexometric titration: Classification, metal ion indicators, masking, and demasking reagents, estimation of Magnesium sulphate, and calcium, Mohr's method, Volhard's, Modified, Scanned with CamScanner
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1, PHARMACEUTICAL, ANALYSIS, INTRODUCTION, Concept of Pharmaceutical Analysis:-, Pharmaceutical Analysis is a branch of science, which deals with the qualitative, quantitative and, semiquantitative estimation of given pharmaceutical sample., Chemical analysis is the resolution of a chemical compound into its proximate or ultimate parts., In analytical chemistry, it is of prime importance to gain information about the qualitative and, quantitative composition of substances and chemical species, that is, to find out what a, substance is composed of and exactly how much. Broadly it is divided in three types;, Qualitative analysis:- It may be define as "which analyte present in the given sample". This has, the goal to identify the various components present in the given sample on the basis of physical, and chemical properties such as functional groups, elemental composition and melting point, etc., Quantitative analysis:- It may be define as "How much amount of analyte present in the given, sample". This has the goal to determine the quantity of each component present in the given, sample., Semi-quantitative analysis:- It is the type of analysis which only describe whether the quantity, of impurity present in given sample is below or above the specified limit such as limit tests., SCOPE OF ANALYSIS, The importance of analytical chemistry lies in the fact that it is the foundation pillar of the entire, procedure of drug discovery, isolation, standardization and quality control. The basic, importance of pharmaceutical analysis is its utility in standardization and quality control of, medicines and drug substances to ensure the quality and stability of the final product. Now days, the analytical techniques are popularly used in following fields:, 1. Biological sample estimation., 2., Food determination., 3. Dairy product estimation., 4. Soil study., 5. Forensic determination., 6. Pesticide estimation in food and vegetable., 7. Environmental pollutant determination., 3, Scanned with CamScanner
